To control false positives in gene-gene interaction analysis: two novel conditional entropy-based approaches.

Genome-wide analysis of gene-gene interactions has been recognized as a powerful avenue to identify the missing genetic components that can not be detected by using current single-point association analysis. Recently, several model-free methods (e.g. the commonly used information based metrics and s...

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Bibliographic Details
Main Authors: Xiaoyu Zuo, Shaoqi Rao, An Fan, Meihua Lin, Haoli Li, Xiaolei Zhao, Jiheng Qin
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3858311?pdf=render