Overexpression of Krüppel-Like Factor 4 Suppresses Migration and Invasion of Non-Small Cell Lung Cancer Through c-Jun-NH2-Terminal Kinase/Epithelial-Mesenchymal Transition Signaling Pathway

Overexpression of Krüppel-Like Factor 4 Suppresses Migration and Invasion of Non-Small Cell Lung Cancer Through c-Jun-NH2-Terminal Kinase/Epithelial-Mesenchymal Transition Signaling Pathway

Krüppel-like factor 4 (KLF4) is a transcription factor and plays a vital role in cancer initiation and development. However, the role of Krüppel-like factor 4 in the metastasis of non-small cell lung cancer (NSCLC) is not clear. Here, we demonstrated that the expression of Krüppel-like factor 4 was...

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Bibliographic Details
Main Authors: Yanping Wu, Lianjun Lin, Xiang Wang, Yong Li, Zhonghui Liu, Wei Ye, Weiming Huang, Gang Lin, Haibo Liu, Jixin Zhang, Ting Li, Beilei Zhao, Liping Lv, Jian Li, Nanping Wang, Xinmin Liu
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-01-01
Series:Frontiers in Pharmacology
Subjects:
invasion
Krüppel-like factor 4
metastasis
migration
non-small cell lung cancer
Online Access:https://www.frontiersin.org/article/10.3389/fphar.2019.01512/full

Internet

https://www.frontiersin.org/article/10.3389/fphar.2019.01512/full

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