Studying Huntington’s Disease in Yeast: From Mechanisms to Pharmacological Approaches

Studying Huntington’s Disease in Yeast: From Mechanisms to Pharmacological Approaches

Huntington’s disease (HD) is a neurodegenerative disorder that leads to progressive neuronal loss, provoking impaired motor control, cognitive decline, and dementia. So far, HD remains incurable, and available drugs are effective only for symptomatic management. HD is caused by a mutant form of the...

Full description

Bibliographic Details
Main Authors: Sebastian Hofer, Katharina Kainz, Andreas Zimmermann, Maria A. Bauer, Tobias Pendl, Michael Poglitsch, Frank Madeo, Didac Carmona-Gutierrez
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-09-01
Series:Frontiers in Molecular Neuroscience
Subjects:
Chorea Huntington
huntingtin
drug discovery
disease model
neurodegeneration
apoptosis
Online Access:https://www.frontiersin.org/article/10.3389/fnmol.2018.00318/full

Internet

https://www.frontiersin.org/article/10.3389/fnmol.2018.00318/full

Similar Items