Inhibition of microRNA-30a alleviates vascular remodeling in pulmonary arterial hypertension

Inhibition of microRNA-30a alleviates vascular remodeling in pulmonary arterial hypertension

The excessive and ectopic pulmonary artery smooth muscle cells (PASMCs) are crucial to the pathogenesis of pulmonary arteriole (PA) remodeling in pulmonary arterial hypertension (PAH). We previously found that microRNA (miR)-30a was significantly increased in acute myocardial infarction (AMI) patien...

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Bibliographic Details
Main Authors: Wenrui Ma, Zhihua Qiu, Zeyang Bai, Yong Dai, Chang Li, Xiao Chen, Xiaoxiao Song, Dingyang Shi, Yanzhao Zhou, Yajie Pan, Yuhua Liao, Mengyang Liao, Zihua Zhou
Format: Article
Language:English
Published: Elsevier 2021-12-01
Series:Molecular Therapy: Nucleic Acids
Subjects:
microRNA-30a
pulmonary arterial hypertension
vascular remodeling
pulmonary artery smooth muscle cells
intratracheal delivery
Online Access:http://www.sciencedirect.com/science/article/pii/S2162253121002365

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http://www.sciencedirect.com/science/article/pii/S2162253121002365

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