Cisplatin Induces Bmi-1 and Enhances the Stem Cell Fraction in Head and Neck Cancer

Cisplatin Induces Bmi-1 and Enhances the Stem Cell Fraction in Head and Neck Cancer

Recent evidence has unveiled a subpopulation of highly tumorigenic, multipotent cells capable of self-renewal in head and neck squamous cell carcinomas (HNSCCs). These unique cells, named here cancer stem cells (CSCs), proliferate slowly and might be involved in resistance to conventional chemother...

Full description

Bibliographic Details
Main Authors: Carolina Nör, Zhaocheng Zhang, Kristy A. Warner, Lisiane Bernardi, Fernanda Visioli, Joseph I. Helman, Rafael Roesler, Jacques E. Nör
Format: Article
Language:English
Published: Elsevier 2014-02-01
Series:Neoplasia: An International Journal for Oncology Research
Online Access:http://www.sciencedirect.com/science/article/pii/S1476558614800134

Internet

http://www.sciencedirect.com/science/article/pii/S1476558614800134

Similar Items