Generation and characterization of human induced pluripotent stem cell lines from a familial Alzheimer's disease PSEN1 A246E patient and a non-demented family member bearing wild-type PSEN1

Generation and characterization of human induced pluripotent stem cell lines from a familial Alzheimer's disease PSEN1 A246E patient and a non-demented family member bearing wild-type PSEN1

The induced pluripotent stem cell (iPSC) lines UOWi002-A and UOWi003-A were reprogrammed from dermal fibroblasts via mRNA transfection. Dermal fibroblasts from a 56 year old female caucasian familial Alzheimer's disease patient carrying A246E mutation in the PSEN1 gene (familial AD3, autopsy co...

Full description

Bibliographic Details
Main Authors: Sonia Sanz Muñoz, Rachelle Balez, Mauricio e Castro Cabral-da-Silva, Tracey Berg, Martin Engel, Monique Bax, Dzung Do-Ha, Claire H. Stevens, Mark Greenough, Ashley Bush, Lezanne Ooi
Format: Article
Language:English
Published: Elsevier 2018-08-01
Series:Stem Cell Research
Online Access:http://www.sciencedirect.com/science/article/pii/S1873506118301983

Internet

http://www.sciencedirect.com/science/article/pii/S1873506118301983

Similar Items