Early Post-stroke Activation of Vascular Endothelial Growth Factor Receptor 2 Hinders the Receptor 1-Dependent Neuroprotection Afforded by the Endogenous Ligand

Early Post-stroke Activation of Vascular Endothelial Growth Factor Receptor 2 Hinders the Receptor 1-Dependent Neuroprotection Afforded by the Endogenous Ligand

Vascular endothelial growth factor (VEGF) has long been connected to the development of tissue lesion following ischemic stroke. Contradictory findings either situate VEGF as a promoter of large infarct volumes or as a potential attenuator of damage due to its well documented neuroprotective capabil...

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Bibliographic Details
Main Authors: Alfredo Cárdenas-Rivera, Aura N. Campero-Romero, Yessica Heras-Romero, Andrés Penagos-Puig, Ruth Rincón-Heredia, Luis B. Tovar-y-Romo
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-07-01
Series:Frontiers in Cellular Neuroscience
Subjects:
Axitinib
ischemia
MCAO
stroke
SU1498
VEGF
Online Access:https://www.frontiersin.org/article/10.3389/fncel.2019.00270/full

Internet

https://www.frontiersin.org/article/10.3389/fncel.2019.00270/full

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