Transcriptional Activation of Matricellular Protein Spondin2 (SPON2) by BRG1 in Vascular Endothelial Cells Promotes Macrophage Chemotaxis

The matricellular protein SPON2 plays diverse roles in the development of cardiovascular diseases. SPON2 is expressed in endothelial cells, but its transcription regulation in the context of atherogenesis remains incompletely appreciated. Here we report that SPON2 expression was up-regulated by pro-...

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Bibliographic Details
Main Authors: Nan Li, Shuai Liu, Yuanyuan Zhang, Liming Yu, Yanjiang Hu, Teng Wu, Mingming Fang, Yong Xu
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-08-01
Series:Frontiers in Cell and Developmental Biology
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Online Access:https://www.frontiersin.org/article/10.3389/fcell.2020.00794/full