Dose-dependent changes in neuroinflammatory and arachidonic acid cascade markers with synaptic marker loss in rat lipopolysaccharide infusion model of neuroinflammation

Dose-dependent changes in neuroinflammatory and arachidonic acid cascade markers with synaptic marker loss in rat lipopolysaccharide infusion model of neuroinflammation

<p>Abstract</p> <p>Background</p> <p>Neuroinflammation, caused by six days of intracerebroventricular infusion of bacterial lipopolysaccharide (LPS), stimulates rat brain arachidonic acid (AA) metabolism. The molecular changes associated with increased AA metabolism are...

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Bibliographic Details
Main Authors: Kellom Matthew, Basselin Mireille, Keleshian Vasken L, Chen Mei, Rapoport Stanley I, Rao Jagadeesh S
Format: Article
Language:English
Published: BMC 2012-05-01
Series:BMC Neuroscience
Subjects:
Arachidonic acid
Cytokine
Synapse
Drebrin
Lipopolysaccharide
Synaptophysin
Phospholipase A<sub>2</sub>
Neuroinflammation
NF-κB
Online Access:http://www.biomedcentral.com/1471-2202/13/50

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http://www.biomedcentral.com/1471-2202/13/50

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