Expression of sterol regulatory element-binding transcription factor (SREBF) 2 and SREBF cleavage-activating protein (SCAP) in human atheroma and the association of their allelic variants with sudden cardiac death

Expression of sterol regulatory element-binding transcription factor (SREBF) 2 and SREBF cleavage-activating protein (SCAP) in human atheroma and the association of their allelic variants with sudden cardiac death

<p>Abstract</p> <p>Background</p> <p>Disturbed cellular cholesterol homeostasis may lead to accumulation of cholesterol in human atheroma plaques. Cellular cholesterol homeostasis is controlled by the sterol regulatory element-binding transcription factor 2 (SREBF-2) an...

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Bibliographic Details
Main Authors: Kytömäki Leena, Salenius Juha-Pekka, Vihinen Mauno, Thusberg Janita, Oksala Niku, Järvinen Otso, Kajander Olli A, Ilveskoski Erkki, Mikkelsson Jussi, Karhunen Pekka J, Levula Mari, Fan Yue-Mei, Soini Juhani T, Laaksonen Reijo, Lehtimäki Terho
Format: Article
Language:English
Published: BMC 2008-12-01
Series:Thrombosis Journal
Online Access:http://www.thrombosisjournal.com/content/6/1/17

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http://www.thrombosisjournal.com/content/6/1/17

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