Increased Programmed Death-Ligand 1 is an Early Epithelial Cell Response to Helicobacter pylori Infection.

Helicobacter pylori (H. pylori) is the major risk factor for the development of gastric cancer. Our laboratory has reported that the Sonic Hedgehog (Shh) signaling pathway is an early response to infection that is fundamental to the initiation of H. pylori-induced gastritis. H. pylori also induces p...

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Bibliographic Details
Main Authors: Loryn Holokai, Jayati Chakrabarti, Taylor Broda, Julie Chang, Jennifer A Hawkins, Nambirajan Sundaram, Lydia E Wroblewski, Richard M Peek, Jiang Wang, Michael Helmrath, James M Wells, Yana Zavros
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2019-01-01
Series:PLoS Pathogens
Online Access:https://doi.org/10.1371/journal.ppat.1007468