Immunogenicity of HIV-1 Vaccines Expressing Chimeric Envelope Glycoproteins on the Surface of Pr55 Gag Virus-Like Particles

Immunogenicity of HIV-1 Vaccines Expressing Chimeric Envelope Glycoproteins on the Surface of Pr55 Gag Virus-Like Particles

The HIV-1 envelope glycoprotein (Env) is present on the surface of the virion at a very low density compared to most other enveloped viruses. Substitution of various parts of the stalk domain of Env (gp41) with the corresponding elements from other viral glycoproteins has been shown to increase Env...

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Bibliographic Details
Main Authors: Rosamund Chapman, Michiel van Diepen, Shireen Galant, Elizabeth Kruse, Emmanuel Margolin, Phindile Ximba, Tandile Hermanus, Penny Moore, Nicola Douglass, Anna-Lise Williamson, Edward Rybicki
Format: Article
Language:English
Published: MDPI AG 2020-01-01
Series:Vaccines
Subjects:
hiv-1
vaccine
chimeric
vlp
spike density
envelope
Online Access:https://www.mdpi.com/2076-393X/8/1/54

Internet

https://www.mdpi.com/2076-393X/8/1/54

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