MKL1 defines the H3K4Me3 landscape for NF-κB dependent inflammatory response

Abstract Macrophage-dependent inflammatory response is considered a pivotal biological process that contributes to a host of diseases when aberrantly activated. The underlying epigenetic mechanism is not completely understood. We report here that MKL1 was both sufficient and necessary for p65-depend...

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Bibliographic Details
Main Authors: Liming Yu, Fei Fang, Xin Dai, Huihui Xu, Xiaohong Qi, Mingming Fang, Yong Xu
Format: Article
Language:English
Published: Nature Publishing Group 2017-03-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-017-00301-w