Amplification of USP13 drives non-small cell lung cancer progression mediated by AKT/MAPK signaling

Amplification of USP13 drives non-small cell lung cancer progression mediated by AKT/MAPK signaling

USP13 is emerging as a potential target in cancer therapy. However, the effect of USP13 on tumor progression is controversial. Here we focused on non-small cell lung cancer (NSCLC), a common cancer with high mortality, and studied the role of USP13 in tumor growth. By analysis of multi-level genetic...

Full description

Bibliographic Details
Main Authors: Yue Wu, Yingqiu Zhang, Congcong Liu, Yang Zhang, Duchuang Wang, Shanshan Wang, Yueguang Wu, Fang Liu, Qiong Li, Xiuxiu Liu, Mohamed Y. Zaky, Dong Yan, Shuyan Liu
Format: Article
Language:English
Published: Elsevier 2019-06-01
Series:Biomedicine & Pharmacotherapy
Subjects:
USP13
NSCLC
Amplification
AKT/MAPK signaling
Tumor promoter
Online Access:http://www.sciencedirect.com/science/article/pii/S0753332218383768

Internet

http://www.sciencedirect.com/science/article/pii/S0753332218383768

Similar Items