Chloroquine is a zinc ionophore.

Chloroquine is an established antimalarial agent that has been recently tested in clinical trials for its anticancer activity. The favorable effect of chloroquine appears to be due to its ability to sensitize cancerous cells to chemotherapy, radiation therapy, and induce apoptosis. The present study...

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Bibliographic Details
Main Authors: Jing Xue, Amanda Moyer, Bing Peng, Jinchang Wu, Bethany N Hannafon, Wei-Qun Ding
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4182877?pdf=render