Plasma neurofilament light as a potential biomarker of neurodegeneration in Alzheimer’s disease

Plasma neurofilament light as a potential biomarker of neurodegeneration in Alzheimer’s disease

Abstract Background A growing body of evidence suggests that the plasma concentration of the neurofilament light chain (NfL) might be considered a plasma biomarker for the screening of neurodegeneration in Alzheimer’s disease (AD). Methods With a single molecule array method (Simoa, Quanterix), plas...

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Bibliographic Details
Main Authors: Piotr Lewczuk, Natalia Ermann, Ulf Andreasson, Christian Schultheis, Jana Podhorna, Philipp Spitzer, Juan Manuel Maler, Johannes Kornhuber, Kaj Blennow, Henrik Zetterberg
Format: Article
Language:English
Published: BMC 2018-07-01
Series:Alzheimer’s Research & Therapy
Subjects:
Alzheimer’s disease
Neurofilament light
Biomarker
Plasma
Online Access:http://link.springer.com/article/10.1186/s13195-018-0404-9

Internet

http://link.springer.com/article/10.1186/s13195-018-0404-9

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