Comparison of methods for calculating conditional expectations of sufficient statistics for continuous time Markov chains

<p>Abstract</p> <p>Background</p> <p>Continuous time Markov chains (CTMCs) is a widely used model for describing the evolution of DNA sequences on the nucleotide, amino acid or codon level. The sufficient statistics for CTMCs are the time spent in a state and the number...

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Bibliographic Details
Main Authors: Tataru Paula, Hobolth Asger
Format: Article
Language:English
Published: BMC 2011-12-01
Series:BMC Bioinformatics
Online Access:http://www.biomedcentral.com/1471-2105/12/465