Catalysis-dependent selenium incorporation and migration in the nitrogenase active site iron-molybdenum cofactor

Dinitrogen reduction in the biological nitrogen cycle is catalyzed by nitrogenase, a two-component metalloenzyme. Understanding of the transformation of the inert resting state of the active site FeMo-cofactor into an activated state capable of reducing dinitrogen remains elusive. Here we report the...

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Bibliographic Details
Main Authors: Thomas Spatzal, Kathryn A Perez, James B Howard, Douglas C Rees
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2015-12-01
Series:eLife
Subjects:
Online Access:https://elifesciences.org/articles/11620