Zoledronic acid in vivo increases in vitro proliferation of rat mesenchymal stromal cells

Background and purpose — Bisphosphonates are widely used in the treatment of bone loss, but they might also have positive effects on osteoblastic cells and bone formation. We evaluated the effect of in vivo zoledronic acid (ZA) treatment and possible concomitant effects of ZA and fracture on the ex...

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Bibliographic Details
Main Authors: Terhi J Heino, Jessica J Alm, Heikki J Halkosaari, Ville-Valtteri Välimäki
Format: Article
Language:English
Published: Taylor & Francis Group 2016-07-01
Series:Acta Orthopaedica
Online Access:http://dx.doi.org/10.1080/17453674.2016.1188258