Superior control of HIV-1 replication by CD8+ T cells targeting conserved epitopes: implications for HIV vaccine design.

Superior control of HIV-1 replication by CD8+ T cells targeting conserved epitopes: implications for HIV vaccine design.

A successful HIV vaccine will likely induce both humoral and cell-mediated immunity, however, the enormous diversity of HIV has hampered the development of a vaccine that effectively elicits both arms of the adaptive immune response. To tackle the problem of viral diversity, T cell-based vaccine app...

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Bibliographic Details
Main Authors: Pratima Kunwar, Natalie Hawkins, Warren L Dinges, Yi Liu, Erin E Gabriel, David A Swan, Claire E Stevens, Janine Maenza, Ann C Collier, James I Mullins, Tomer Hertz, Xuesong Yu, Helen Horton
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3669284?pdf=render

Internet

http://europepmc.org/articles/PMC3669284?pdf=render

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