Periodically Pulsed Immunotherapy in a Mathematical Model of Tumor, CD4+ T Cells, and Antitumor Cytokine Interactions

Immunotherapy is one of the most recent approaches for controlling and curing malignant tumors. In this paper, we consider a mathematical model of periodically pulsed immunotherapy using CD4+ T cells and an antitumor cytokine. Mathematical analyses are performed to determine the threshold of a succe...

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Bibliographic Details
Main Authors: Hsiu-Chuan Wei, Jui-Ling Yu, Chia-Yu Hsu
Format: Article
Language:English
Published: Hindawi Limited 2017-01-01
Series:Computational and Mathematical Methods in Medicine
Online Access:http://dx.doi.org/10.1155/2017/2906282