Culture independent analysis using gnd as a target gene to assess Escherichia coli diversity and community structure

Abstract Current culture methods to investigate changes in Escherichia coli community structure are often slow and laborious. Genes such as gnd (6-phosphogluconate dehydrogenase) have a highly variable nucleotide sequence and may provide a target for E. coli microbiome analysis using culture-indepen...

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Bibliographic Details
Main Authors: Adrian L. Cookson, Patrick J. Biggs, Jonathan C. Marshall, Angela Reynolds, Rose M. Collis, Nigel P. French, Gale Brightwell
Format: Article
Language:English
Published: Nature Publishing Group 2017-04-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-017-00890-6