https://www.emjreviews.com/allergy-immuThe 'Nucleolus' Hypothesis of Autoimmune Diseases and Its Implications

Many autoimmune diseases, such as lupus and Sjögren’s syndrome, have a female bias and adult onset. One possible explanation for this bias is disruption of the inactive X chromosome, which is a major epigenetic feature in female cells. Indeed, only one X chromosome is needed in male and female somat...

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Bibliographic Details
Main Authors: Wesley H. Brooks, Yves Renaudineau
Format: Article
Language:English
Published: European Medical Journal 2017-06-01
Series:European Medical Journal
Subjects:
Online Access:https://www.emjreviews.com/allergy-immunology/article/the-nucleolus-hypothesis-of-autoimmune-diseases-and-its-implications/