Hepatocyte growth factor is necessary for efficient outgrowth of injured peripheral axons in in vitro culture system and in vivo nerve crush mouse model

Hepatocyte growth factor is necessary for efficient outgrowth of injured peripheral axons in in vitro culture system and in vivo nerve crush mouse model

Hepatocyte growth factor (HGF) is a neurotrophic factor and its role in peripheral nerves has been relatively unknown. In this study, biological functions of HGF and its receptor c-met have been investigated in the context of regeneration of damaged peripheral nerves. Axotomy of the peripheral branc...

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Bibliographic Details
Main Authors: Nayeon Lee, Sang Hwan Lee, Junghun Lee, Mi-Young Lee, Jaegook Lim, Subin Kim, Sunyoung Kim
Format: Article
Language:English
Published: Elsevier 2021-07-01
Series:Biochemistry and Biophysics Reports
Subjects:
HGF
c-met
Sensory neuron
Neurite outgrowth
Axon regeneration
Peripheral neuropathy
Online Access:http://www.sciencedirect.com/science/article/pii/S2405580821000674

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http://www.sciencedirect.com/science/article/pii/S2405580821000674

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