Genome-wide association analysis confirms and extends the association of SLC2A9 with serum uric acid levels to Mexican Americans

Genome-wide association analysis confirms and extends the association of SLC2A9 with serum uric acid levels to Mexican Americans

Increased serum uric acid (SUA) is a risk factor for gout and renal and cardiovascular disease. The purpose of this study was to identify genetic factors that affect the variation in SUA in 632 Mexican Americans participants of the San Antonio Family Heart Study (SAFHS). A genome-wide association an...

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Bibliographic Details
Main Authors: Venkata Saroja eVoruganti, Jack W Kent, Subrata eDebnath, Shelley A Cole, Karin eHaack, Harald HH Goring, Melanie A Carless, Joanne E Curran, Matthew P Johnson, Laura eAlmasy, Thomas D Dyer, Jean W MacCluer, Eric K Moses, Hanna E Abboud, Michael C Mahaney, John eBlangero, Anthony Gean Comuzzie
Format: Article
Language:English
Published: Frontiers Media S.A. 2013-12-01
Series:Frontiers in Genetics
Subjects:
Hyperuricemia
kinship
effect size
Variance components decomposition approach
Joint linkage/association analysis
Online Access:http://journal.frontiersin.org/Journal/10.3389/fgene.2013.00279/full

Internet

http://journal.frontiersin.org/Journal/10.3389/fgene.2013.00279/full

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