cGAMP Promotes Germinal Center Formation and Production of IgA in Nasal-Associated Lymphoid Tissue

cGAMP Promotes Germinal Center Formation and Production of IgA in Nasal-Associated Lymphoid Tissue

Induction of immunoglobulin (Ig) A in the mucosa of the upper respiratory tract and the nasal cavity protects against influenza virus infection. Cyclic dinucleotides (CDNs) are used as mucosal adjuvants to enhance the immunogenicity of intranasal influenza hemagglutinin (HA) vaccines. The adjuvant a...

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Bibliographic Details
Main Authors: Hiromi Takaki, Ken Takashima, Hiroyuki Oshiumi, Akira Ainai, Tadaki Suzuki, Hideki Hasegawa, Misako Matsumoto, Tsukasa Seya
Format: Article
Language:English
Published: MDPI AG 2017-12-01
Series:Medical Sciences
Subjects:
IgA
NALT
cGAMP
STING
Online Access:https://www.mdpi.com/2076-3271/5/4/35

Internet

https://www.mdpi.com/2076-3271/5/4/35

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