A Fiber Alginate Co-culture Platform for the Differentiation of mESC and Modeling of the Neural Tube

Alginate hydrogels are a commonly used substrate for in vitro 3D cell culture. These naturally derived biomaterials are highly tunable, biocompatible, and can be designed to mimic the elastic modulus of the adult brain at 1% w/v solution. Recent studies show that the molecular weight of the alginate...

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Bibliographic Details
Main Authors: Orla M. Fannon, Angela Bithell, Benjamin J. Whalley, Evangelos Delivopoulos
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-01-01
Series:Frontiers in Neuroscience
Subjects:
Online Access:https://www.frontiersin.org/articles/10.3389/fnins.2020.524346/full