Identification of new therapeutic targets by genome-wide analysis of gene expression in the ipsilateral cortex of aged rats after stroke.

Because most human stroke victims are elderly, studies of experimental stroke in the aged rather than the young rat model may be optimal for identifying clinically relevant cellular responses, as well for pinpointing beneficial interventions.We employed the Affymetrix platform to analyze the whole-g...

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Bibliographic Details
Main Authors: Ana-Maria Buga, Claus Jürgen Scholz, Senthil Kumar, James G Herndon, Dragos Alexandru, Gabriel Radu Cojocaru, Thomas Dandekar, Aurel Popa-Wagner
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3521001?pdf=render