The downregulation of IL-18R defines bona fide kidney-resident CD8+ T cells

The downregulation of IL-18R defines bona fide kidney-resident CD8+ T cells

Summary: Stepwise induction of CD69 and CD103 marks distinct differentiation stages of mucosal Trms. But the majority of non-mucosal Trm lacks CD103 expression. The expression of CD69 alone cannot faithfully define Trm cells in heavily vascularized non-mucosal tissues, such as the kidney. Here, we f...

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Bibliographic Details
Main Authors: Wei Liao, Yong Liu, Chaoyu Ma, Liwen Wang, Guo Li, Shruti Mishra, Saranya Srinivasan, Kenneth Ka-Ho Fan, Haijing Wu, Qianwen Li, Ming Zhao, Xun Liu, Erika L. Demel, Xin Zhang, Yuanzheng Qiu, Qianjin Lu, Nu Zhang
Format: Article
Language:English
Published: Elsevier 2021-01-01
Series:iScience
Subjects:
Immunology
Cell Biology
Transcriptomics
Online Access:http://www.sciencedirect.com/science/article/pii/S258900422031172X

Internet

http://www.sciencedirect.com/science/article/pii/S258900422031172X

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