In Silico Docking and In Vitro Approaches towards BACE1 and Cholinesterases Inhibitory Effect of Citrus Flavanones

In Silico Docking and In Vitro Approaches towards BACE1 and Cholinesterases Inhibitory Effect of Citrus Flavanones

Alzheimer’s disease (AD) is the most prevalent neurodegenerative disease, distinctively characterized by senile plaques, neurofibrillary tangles, and synaptic loss, finally resulting in neuronal death. β-Site amyloid precursor protein (APP) cleaving enzyme 1 (BACE1) and cholineste...

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Bibliographic Details
Main Authors: Seungeun Lee, Kumju Youn, GyuTae Lim, Jinhyuk Lee, Mira Jun
Format: Article
Language:English
Published: MDPI AG 2018-06-01
Series:Molecules
Subjects:
Alzheimer’s disease
BACE1
cholinesterases
in silico docking
citrus flavanones
hesperidin
Online Access:http://www.mdpi.com/1420-3049/23/7/1509

Internet

http://www.mdpi.com/1420-3049/23/7/1509

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