NUDT7 Loss Promotes <i>Kras<sup>G12D</sup> </i>CRC Development

NUDT7 Loss Promotes <i>Kras<sup>G12D</sup> </i>CRC Development

Studies have suggested that dysregulation of peroxisomal lipid metabolism might play an important role in colorectal cancer (CRC) development. Here, we found that <i>Kras<sup>G12D</sup></i>-driven CRC tumors demonstrate dysfunctional peroxisomal b-oxidation and identified <...

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Bibliographic Details
Main Authors: Jinsoo Song, Sujeong Park, Jinjoo Oh, Deokha Kim, Ji Hyun Ryu, Won Cheol Park, In-Jeoung Baek, Xi Cheng, Xin Lu, Eun-Jung Jin
Format: Article
Language:English
Published: MDPI AG 2020-03-01
Series:Cancers
Subjects:
peroxisome
colorectal cancer
peroxisomal coenzyme a diphosphatase nudt7 (nudt7)
palmitic acid
β-catenin
Online Access:https://www.mdpi.com/2072-6694/12/3/576

Internet

https://www.mdpi.com/2072-6694/12/3/576

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