Expression profiling of a genetic animal model of depression reveals novel molecular pathways underlying depressive-like behaviours.

The Flinders model is a validated genetic rat model of depression that exhibits a number of behavioural, neurochemical and pharmacological features consistent with those observed in human depression.In this study we have used genome-wide microarray expression profiling of the hippocampus and prefron...

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Main Authors: Ekaterini Blaveri, Fiona Kelly, Alessandra Mallei, Kriss Harris, Adam Taylor, Juliet Reid, Maria Razzoli, Lucia Carboni, Chiara Piubelli, Laura Musazzi, Girogio Racagni, Aleksander Mathé, Maurizio Popoli, Enrico Domenici, Stewart Bates
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2010-09-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC2935375?pdf=render