Antibiotics as selectors and accelerators of diversity in the mechanisms of resistance: From the resistome to genetic plasticity in the beta-lactamases world

Antibiotics as selectors and accelerators of diversity in the mechanisms of resistance: From the resistome to genetic plasticity in the beta-lactamases world

Antibiotics and antibiotic resistance determinants, natural molecules closely related to bacterial physiology and consistent with an ancient origin, are not only present in antibiotic-producing bacteria. Throughput sequencing technologies have revealed an unexpected reservoir of antibiotic resistanc...

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Bibliographic Details
Main Authors: Juan- Carlos eGalán, Fernando eGonzalez-Candelas, Jean-Marc eRolain, Rafael eCanton
Format: Article
Language:English
Published: Frontiers Media S.A. 2013-02-01
Series:Frontiers in Microbiology
Subjects:
plasticity
Environmental resistome
intrinsic resistome
-lactamase
review.
OXA-beta-lactamase
Online Access:http://journal.frontiersin.org/Journal/10.3389/fmicb.2013.00009/full

Internet

http://journal.frontiersin.org/Journal/10.3389/fmicb.2013.00009/full

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