Conservation of gene cassettes among diverse viruses of the human gut.

Viruses are a crucial component of the human microbiome, but large population sizes, high sequence diversity, and high frequencies of novel genes have hindered genomic analysis by high-throughput sequencing. Here we investigate approaches to metagenomic assembly to probe genome structure in a sample...

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Bibliographic Details
Main Authors: Samuel Minot, Gary D Wu, James D Lewis, Frederic D Bushman
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3416800?pdf=render