Astrocytes Resist HIV-1 Fusion but Engulf Infected Macrophage Material

Astrocytes Resist HIV-1 Fusion but Engulf Infected Macrophage Material

HIV-1 disseminates to diverse tissues and establishes long-lived viral reservoirs. These reservoirs include the CNS, in which macrophage-lineage cells, and as suggested by many studies, astrocytes, may be infected. Here, we have investigated astrocyte infection by HIV-1. We confirm that astrocytes t...

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Bibliographic Details
Main Authors: Rebecca A. Russell, Jakub Chojnacki, Daniel M. Jones, Errin Johnson, Thao Do, Christian Eggeling, Sergi Padilla-Parra, Quentin J. Sattentau
Format: Article
Language:English
Published: Elsevier 2017-02-01
Series:Cell Reports
Subjects:
HIV-1
astrocyte
fusion
macrophage
phagocytosis
brain
Online Access:http://www.sciencedirect.com/science/article/pii/S2211124717300645

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http://www.sciencedirect.com/science/article/pii/S2211124717300645

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