Innate immunity drives the initiation of a murine model of primary biliary cirrhosis.

Innate immunity drives the initiation of a murine model of primary biliary cirrhosis.

Invariant natural killer T (iNKT) cells play complex roles in bridging innate and adaptive immunity by engaging with glycolipid antigens presented by CD1d. Our earlier work suggested that iNKT cells were involved in the initiation of the original loss of tolerance in primary biliary cirrhosis (PBC)....

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Bibliographic Details
Main Authors: Chao-Hsuan Chang, Ying-Chun Chen, Weici Zhang, Patrick S C Leung, M Eric Gershwin, Ya-Hui Chuang
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4373957?pdf=render

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http://europepmc.org/articles/PMC4373957?pdf=render

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