Personalized Medicine for PLA2R1-Related Membranous Nephropathy: A Multicenter Randomized Control Trial

Personalized Medicine for PLA2R1-Related Membranous Nephropathy: A Multicenter Randomized Control Trial

Background: Membranous Nephropathy (MN) is a rare autoimmune disease related to PLA2R1 antibodies in 70% of cases. One third of patients enter in spontaneous remission. PLA2R1 epitopes in MN have been characterized in four different domains of PLA2R1 and a mechanism of epitope spreading from the imm...

Full description

Bibliographic Details
Main Authors: Vesna Brglez, Sonia Boyer-Suavet, Kévin Zorzi, Céline Fernandez, Eric Fontas, Vincent Esnault, Barbara Seitz-Polski
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-08-01
Series:Frontiers in Medicine
Subjects:
membranous nephropathy
PLA2R1
epitope spreading
rituximab
personalized treatment
randomized prospective trial
Online Access:https://www.frontiersin.org/article/10.3389/fmed.2020.00412/full

Internet

https://www.frontiersin.org/article/10.3389/fmed.2020.00412/full

Similar Items