Increased H3K4me3 methylation and decreased miR-7113-5p expression lead to enhanced Wnt/β-catenin signaling in immune cells from PTSD patients leading to inflammatory phenotype

Increased H3K4me3 methylation and decreased miR-7113-5p expression lead to enhanced Wnt/β-catenin signaling in immune cells from PTSD patients leading to inflammatory phenotype

Abstract Background Posttraumatic stress disorder (PTSD) is a psychiatric disorder accompanied by chronic peripheral inflammation. What triggers inflammation in PTSD is currently unclear. In the present study, we identified potential defects in signaling pathways in peripheral blood mononuclear cell...

Full description

Bibliographic Details
Main Authors: Marpe Bam, Xiaoming Yang, Brandon P. Busbee, Allison E. Aiello, Monica Uddin, Jay P. Ginsberg, Sandro Galea, Prakash S. Nagarkatti, Mitzi Nagarkatti
Format: Article
Language:English
Published: BMC 2020-11-01
Series:Molecular Medicine
Online Access:http://link.springer.com/article/10.1186/s10020-020-00238-3

Internet

http://link.springer.com/article/10.1186/s10020-020-00238-3

Similar Items