Overexpression of angiotensinogen downregulates aquaporin 1 expression via modulation of Nrf2–HO-1 pathway in renal proximal tubular cells of transgenic mice

Overexpression of angiotensinogen downregulates aquaporin 1 expression via modulation of Nrf2–HO-1 pathway in renal proximal tubular cells of transgenic mice

Introduction: We aimed to examine the regulation of aquaporin 1 expression in an angiotensinogen transgenic mouse model, focusing on underlying mechanisms. Methods: Male transgenic mice overexpressing rat angiotensinogen in their renal proximal tubular cells (RPTCs) and rat immortalised RPTCs stably...

Full description

Bibliographic Details
Main Authors: Shiao-Ying Chang, Chao-Sheng Lo, Xin-Ping Zhao, Min-Chun Liao, Isabelle Chenier, Richard Bouley, Julie R Ingelfinger, John SD Chan, Shao-Ling Zhang
Format: Article
Language:English
Published: Hindawi - SAGE Publishing 2016-09-01
Series:Journal of the Renin-Angiotensin-Aldosterone System
Online Access:https://doi.org/10.1177/1470320316668737

Internet

https://doi.org/10.1177/1470320316668737

Similar Items