Tenascin C promiscuously binds growth factors via its fifth fibronectin type III-like domain.

Tenascin C (TNC) is an extracellular matrix protein that is upregulated during development as well as tissue remodeling. TNC is comprised of multiple independent folding domains, including 15 fibronectin type III-like (TNCIII) domains. The fifth TNCIII domain (TNCIII5) has previously been shown to b...

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Bibliographic Details
Main Authors: Laura De Laporte, Jeffrey J Rice, Federico Tortelli, Jeffrey A Hubbell
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/23637968/?tool=EBI