The protective effect of dronedarone on the structure and mechanical properties of the aorta in hypertensive rats by decreasing the concentration of symmetric dimethylarginine (SDMA).

BACKGROUND AND AIMS:Dronedarone is a new multichannel-blocking antiarrhythmic for the treatment of patients with atrial fibrillation. Our group has demonstrated that dronedarone produces regression of cardiac remodeling; however, its effect on the remodeling of the elastic arteries has not yet been...

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Main Authors: Begoña Quintana-Villamandos, María Del Carmen González, María Jesús Delgado-Martos, Perla Yareli Gutiérrez-Arzapalo, Rainer H Böger, Nicole Lüneburg, David Muñoz, Emilio Delgado-Baeza
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2019-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0216820