Histological Regression of Giant Cell Tumor of Bone Following RANK Ligand Inhibition

Lung metastases are a rare complication of giant cell tumors of bone. We herein describe an interesting case of histological regression and size reduction of lung metastases originating from a primary giant cell tumor of bone in response to the RANK ligand inhibitor denosumab.

Bibliographic Details
Main Authors: Martin F. Dietrich MD, PhD, Dominick Cavuoti MD, Michael Landay MD, Yull E. Arriaga MD
Format: Article
Language:English
Published: SAGE Publishing 2014-11-01
Series:Journal of Investigative Medicine High Impact Case Reports
Online Access:https://doi.org/10.1177/2324709614560216