Lignans from <i>Bursera fagaroides</i> Affect In Vivo Cell Behavior by Disturbing the Tubulin Cytoskeleton in Zebrafish Embryos

Lignans from <i>Bursera fagaroides</i> Affect In Vivo Cell Behavior by Disturbing the Tubulin Cytoskeleton in Zebrafish Embryos

By using a zebrafish embryo model to guide the chromatographic fractionation of antimitotic secondary metabolites, seven podophyllotoxin-type lignans were isolated from a hydroalcoholic extract obtained from the steam bark of <i>Bursera fagaroides</i>. The compounds were identified as po...

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Bibliographic Details
Main Authors: Mayra Antúnez-Mojica, Andrés M. Rojas-Sepúlveda, Mario A. Mendieta-Serrano, Leticia Gonzalez-Maya, Silvia Marquina, Enrique Salas-Vidal, Laura Alvarez
Format: Article
Language:English
Published: MDPI AG 2018-12-01
Series:Molecules
Subjects:
<i>Bursera fagaroides</i>
podophyllotoxin-type lignans
cell cycle
cell migration
epiboly
microtubules
F-actin
cancer
lignans
Online Access:https://www.mdpi.com/1420-3049/24/1/8

Internet

https://www.mdpi.com/1420-3049/24/1/8

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