Integrative Analysis of Gene Expression Data by RNA Sequencing for Differential Diagnosis of Acute Leukemia: Potential Application of Machine Learning

Integrative Analysis of Gene Expression Data by RNA Sequencing for Differential Diagnosis of Acute Leukemia: Potential Application of Machine Learning

BCR-ABL1–positive acute leukemia can be classified into three disease categories: B-lymphoblastic leukemia (B-ALL), acute myeloid leukemia (AML), and mixed-phenotype acute leukemia (MPAL). We conducted an integrative analysis of RNA sequencing (RNA-seq) data obtained from 12 BCR-ABL1–positive B-ALL,...

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Bibliographic Details
Main Authors: Jaewoong Lee, Sungmin Cho, Seong-Eui Hong, Dain Kang, Hayoung Choi, Jong-Mi Lee, Jae-Ho Yoon, Byung-Sik Cho, Seok Lee, Hee-Je Kim, Myungshin Kim, Yonggoo Kim
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-08-01
Series:Frontiers in Oncology
Subjects:
BCR-ABL1
mixed-phenotype acute leukemia
RNA sequencing
gene fusion
mutation
expression
Online Access:https://www.frontiersin.org/articles/10.3389/fonc.2021.717616/full

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https://www.frontiersin.org/articles/10.3389/fonc.2021.717616/full

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