Bone marrow donor selection and characterization of MSCs is critical for pre-clinical and clinical cell dose production

Bone marrow donor selection and characterization of MSCs is critical for pre-clinical and clinical cell dose production

Abstract Background Cell based therapies, such as bone marrow derived mesenchymal stem cells (BM-MSCs; also known as mesenchymal stromal cells), are currently under investigation for a number of disease applications. The current challenge facing the field is maintaining the consistency and quality o...

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Bibliographic Details
Main Authors: Alpa Trivedi, Byron Miyazawa, Stuart Gibb, Kristen Valanoski, Lindsay Vivona, Maximillian Lin, Daniel Potter, Mars Stone, Philip J. Norris, James Murphy, Sawyer Smith, Martin Schreiber, Shibani Pati
Format: Article
Language:English
Published: BMC 2019-04-01
Series:Journal of Translational Medicine
Subjects:
Stem cell therapy
Bioprocessing
Viability
Differentiation
Donor variability
Online Access:http://link.springer.com/article/10.1186/s12967-019-1877-4

Internet

http://link.springer.com/article/10.1186/s12967-019-1877-4

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