Malaria parasite CelTOS targets the inner leaflet of cell membranes for pore-dependent disruption

Apicomplexan parasites contain a conserved protein CelTOS that, in malaria parasites, is essential for traversal of cells within the mammalian host and arthropod vector. However, the molecular role of CelTOS is unknown because it lacks sequence similarity to proteins of known function. Here, we dete...

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Bibliographic Details
Main Authors: John R Jimah, Nichole D Salinas, Monica Sala-Rabanal, Nathaniel G Jones, L David Sibley, Colin G Nichols, Paul H Schlesinger, Niraj H Tolia
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2016-12-01
Series:eLife
Subjects:
Online Access:https://elifesciences.org/articles/20621