Multiple novel gene-by-environment interactions modify the effect of FTO variants on body mass index

Common variants in the fat mass and obesity associated (FTO) gene are linked to body mass index (BMI). Using the latest UK Biobank data, this study shows novel gene x environment interactions between FTOand lifestyle factors, including frequency of alcohol consumption, sleep, and added dietary salt.

Bibliographic Details
Main Authors: Alexander I. Young, Fabian Wauthier, Peter Donnelly
Format: Article
Language:English
Published: Nature Publishing Group 2016-09-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/ncomms12724