Longitudinal predictive modeling of tau progression along the structural connectome

Tau neurofibrillary tangles, a pathophysiological hallmark of Alzheimer’s disease (AD), exhibit a stereotypical spatiotemporal trajectory that is strongly correlated with disease progression and cognitive decline. Personalized prediction of tau progression is, therefore, vital for the early diagnosi...

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Bibliographic Details
Main Authors: Fan Yang, Samadrita Roy Chowdhury, Heidi I.L. Jacobs, Jorge Sepulcre, Van J. Wedeen, Keith A. Johnson, Joyita Dutta
Format: Article
Language:English
Published: Elsevier 2021-08-01
Series:NeuroImage
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S1053811921004031