Amyloid-beta-dependent phosphorylation of collapsin response mediator protein-2 dissociates kinesin in Alzheimer's disease

Amyloid-beta-dependent phosphorylation of collapsin response mediator protein-2 dissociates kinesin in Alzheimer's disease

Alzheimer's disease (AD) is a neurodegenerative disorder characterized by accumulation of amyloid plaques and neurofibrillary tangles. Prior to the development of these characteristic pathological hallmarks of AD, anterograde axonal transport is impaired. However, the key proteins that initiate...

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Bibliographic Details
Main Authors: Sara H Mokhtar, Min Joung Kim, Kylie A Magee, Pei Mun Aui, Speros Thomas, Maha M Bakhuraysah, Amani A Alrehaili, Jae Young Lee, David L Steer, Rachel Kenny, Catriona McLean, Michael F Azari, Antonis Birpanagos, Ewlina Lipiec, Philip Heraud, Bayden Wood, Steven Petratos
Format: Article
Language:English
Published: Wolters Kluwer Medknow Publications 2018-01-01
Series:Neural Regeneration Research
Subjects:
amyloid-beta protein; kinases; collapsin response mediator protein; microtubules; kinesin; tubulin
Online Access:http://www.nrronline.org/article.asp?issn=1673-5374;year=2018;volume=13;issue=6;spage=1066;epage=1080;aulast=Mokhtar

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http://www.nrronline.org/article.asp?issn=1673-5374;year=2018;volume=13;issue=6;spage=1066;epage=1080;aulast=Mokhtar

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