Regulation of mitochondrial ceramide distribution by members of the BCL-2 family[S]

Apoptosis is an intricately regulated cellular process that proceeds through different cell type- and signal-dependent pathways. In the mitochondrial apoptotic program, mitochondrial outer membrane permeabilization by BCL-2 proteins leads to the release of apoptogenic factors, caspase activation, an...

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Bibliographic Details
Main Authors: Tejia Zhang, Lauren Barclay, Loren D. Walensky, Alan Saghatelian
Format: Article
Language:English
Published: Elsevier 2015-08-01
Series:Journal of Lipid Research
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S0022227520355279